High Cholesterol, Familial Homozygous research, articles, guidelines & medical evidence database search.
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All Pubmed data courtesy of the U.S. National Library of Medicine. Library last updated 20 December 2020.
Clinical trials databases last updated 1 December 2020 (clinicaltrials.gov) and 1 December 2020 (ictrp)
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Research
The LDL receptor locus in familial hypercholesterolemia: multiple mutations disrupt transport and processing of a membrane receptor.
Tolleshaug H, Hobgood K K, Brown M S, Goldstein J L
Cell Vol 32(3)
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Date 01 Mar 1983
Research
Posttranslational processing of the LDL receptor and its genetic disruption in familial hypercholesterolemia.
Tolleshaug H, Goldstein J L, Schneider W J, Brown M S
Cell Vol 30(3)
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Date 01 Oct 1982
Research
Analysis of a mutant strain of human fibroblasts with a defect in the internalization of receptor-bound low density lipoprotein.
Brown M S, Goldstein J L
Cell Vol 9(4 PT 2)
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Date 01 Dec 1976
Research
Release of low density lipoprotein from its cell surface receptor by sulfated glycosaminoglycans.
Goldstein J L, Basu S K, Brunschede G Y, Brown M S
Cell Vol 7(1)
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Date 01 Jan 1976
Research
Homozygous familial hypercholesterolemia. A possible biochemical explanation of clinical heterogeneity.
Breslow J L, Spaulding D R, Lux S E, Levy R I, Lees R S
The New England journal of medicine Vol 293(18)
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Date 30 Oct 1975
Research
Detection of familial hypercholesterolemia by assaying functional low-density-lipoprotein receptors on lymphocytes.
Cuthbert J A, East C A, Bilheimer D W, Lipsky P E
The New England journal of medicine Vol 314(14)
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Date 03 Apr 1986
Research
Reduction of serum cholesterol in Watanabe rabbits by xenogeneic hepatocellular transplantation.
Gunsalus J R, Brady D A, Coulter S M, Gray B M, Edge A S
Nature medicine Vol 3(1)
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Date 01 Jan 1997
Research
A Drug Screen using Human iPSC-Derived Hepatocyte-like Cells Reveals Cardiac Glycosides as a Potential Treatment for Hypercholesterolemia.
Cayo Max A, Mallanna Sunil K, Di Furio Francesca, Jing Ran, Tolliver Lauren B ...
Cell stem cell Vol 20(4)
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Date 06 Apr 2017
Research
Normalization of low-density lipoprotein receptor expression in receptor defective homozygous familial hypercholesterolemia by inhibition of PCSK9 wit...
Lambert Gilles, Chatelais Mathias, Petrides Francine, Passard Maxime, Thedrez Aurélie ...
Journal of the American College of Cardiology Vol 64(21)
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Date 02 Dec 2014
Research
Failure of a slow channel calcium antagonist, verapamil, to retard atherosclerosis in the Watanabe heritable hyperlipidemic rabbit: an animal model of...
Tilton G D, Buja L M, Bilheimer D W, Apprill P, Ashton J ...
Journal of the American College of Cardiology Vol 6(1)
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Date 01 Jul 1985
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